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Many patients experience a negative impact on work productivity and employment status after a diagnosis of myeloproliferative neoplasm (MPN), according to a study published in BMC Cancer. The clinical adverse effects of MPNs (eg, polycythemia vera [PV], essential thrombocytopenia [ET], myelofibrosis [MF]) are well known; risks for cardiovascular and thrombotic events [...]
Mon, May 14, 2018, Continue reading at the source
To date, the JAK inhibitor ruxolitinib (Jakafi) is the only FDA-approved therapy for the treatment of patients with myelofibrosis (MF); however, novel agents and combination regimens are in development to address some of the unmet needs in MF, including treating cases of anemia associated with MF and treatment with ruxolitinib, [...]
Mon, Apr 30, 2018, Continue reading at the source
Dr. Gabriela Hobbs One of the most exciting aspects of clinical research is translating lab-based discoveries into tests and treatments that can be used in daily clinical practice. The last 2 decades have yielded an explosive amount of information about the genetics of hematologic malignancies, as well as targeted therapies based on [...]
Mon, Apr 30, 2018, Continue reading at the source
The applications for the second found of MF Challenge funding will be reviewed on Friday, May 31st in Chicago. In addition to members of the Foundation's Scientific Advisory Board, thought leaders from fibrosis will be joining the review panel as the proposals are judged. In addition to scientific merit, the [...]
Sun, May 26, 2013, Continue reading at the source

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