PV Reporter and MPN Cancer Connection are partnering with Imerman Angels and the Cleveland Clinic 4th Angel Mentoring Program to better serve the needs of our growing community. We are very excited to announce these FREE support programs as we continue providing easy access to an expanding network of organizations serving the MPN community – […]
MPN patients have higher risk of Inflammatory Bowel Disease
What’s the difference between IBS and IBD? IBS is a disorder of the gastrointestinal (GI) tract. IBD is inflammation or destruction of the bowel wall, which can lead to sores and narrowing of the intestines. Abstract: An association between hematological cancers and inflammatory bowel disease (IBD) has previously been suggested, but the risk of IBD […]
Polycythemia Vera patient advocate on living with MPN, Diane’s story
September Blood Cancer Awareness Month Spotlight by David Wallace David Wallace, your host with PV Reporter, talks to fellow PV patient advocate Diane Rose about living with Polycythemia Vera. Diane shares her patient story as we talk about how she was diagnosed, treatment, ET shifting to PV, being your own advocate, fear of needles and […]
06: My Plan to beat Coronavirus Blues
MPN Chronicles Podcast by David Wallace I started 2020 with a goal to lose weight before the pandemic reared its ugly head. I changed the way I was eating, lobbied my hematologist for a change in PV meds (no more Rux/Peg combo, just Pegasys) and I started walking again. When Covid hit, I decided to […]
Best Mobile Apps for MPN Cancer Patients
by Deb Wesloh & Lou Ann Donovan Apps can help Manage your Life with Cancer Mobile applications for smartphones and tablets, also known as apps, are becoming a rising resource to help people with cancer manage their day-to-day life. Apps are also an easy resource for family members to stay informed and provide support for […]
Differential cytokine network profile in Polycythemia Vera and Secondary Polycythemia
Authors: Maira da Costa Cacemiro, Juçara Gastaldi Cominal, Maria Gabriela Berzoti-Coelho, Raquel Tognon, Natalia de Souza Nunes, Belinda Simões, Ítalo Sousa Pereira, Daniela Carlos, Lucia Helena Faccioli, Lorena Lobo de Figueiredo-Pontes, Fabiani Gai Frantz & Fabíola Attié de Castro Scientific Reports volume 10, Article number: 7032 (2020) Abstract Polycythemia vera (PV) is a clonal disorder resulting from neoplastic transformation of hematopoietic stem cells, while secondary polycythemia (SP) is a disease characterized by increased absolute […]
Immunotherapy in Myeloproliferative Diseases
by Lukas M. Braun 1,2 and Robert Zeiser 1,3,4,5,* 1 Department of Medicine I, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; lukas.braun@uniklinik-freiburg.de 2 Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany 3 German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany 4 […]
PTG-300 Hepcidin Mimetic Receives FDA Orphan Drug Designation for Treatment of Polycythemia Vera
NEWARK, Calif., June 17, 2020 /PRNewswire/ — Protagonist Therapeutics, Inc. (Nasdaq: PTGX) today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for PTG-300 for the treatment of polycythemia vera. PTG-300 is an injectable synthetic peptide mimetic of the natural hormone hepcidin currently in clinical development for the treatment of polycythemia vera and hereditary hemochromatosis. “Receiving […]
MPN Hub Launches Open Access Resource
by David Wallace The MPN Hub is an “open-access” online resource, dedicated to providing balanced, credible, and up-to-date medical education in MPN. The aim is to enhance knowledge in MPN, through the multichannel dissemination of global advances related to their classification, diagnosis, treatment, and management. The MPN Hub shares new data, evidence-based articles, therapy approvals, […]
MPN Specialist Explains PTG-300 and Clinical Trial for PV Patients
by David Wallace Hepcidin Mimetic PTG-300 Promising Treatment for PV How does PTG-300 work to reduce or eliminate the need for phlebotomy in PV? How does iron deficiency play a role in polycythemia vera? What are the goals of this treatment? Leading MPN expert, Dr. Srdan Verstovsek, from MD Anderson Cancer Center, interviews with David […]
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