The Fleischman Lab Continues Investigating the Role of Inflammation in MPN

2015 MPN Research Update by Dr. Angela Fleischman We are continuing to work on the role of inflammation in MPN.  The human immune system turns on the immune response when it recognizes invaders such as bacteria or viruses by producing inflammatory proteins, also called cytokines.  Cytokines are helpful to fight infection but if the immune […]

A key role for lymphoid cells in the pathology of myeloproliferative neoplasm

Publisher’s Note In early July, we reported The MPN Research Foundation and LLS granted $1 million research funding for MPNs.  Dr Angela Fleischman has been a key contributor to PV Reporter and was one of the MPN Challenge award winners.  I asked her for a description of the research they will be working on and she […]

Synopsis of ASH 2013 Abstract – Peginvera study

by Dr. Angela Fleischman Synopsis of ASH 2013 Abstract: “Analysis of Molecular Responses and Chromosomal Aberrations in patients with PV treated with Peg-Proline-Interferon Alpha-2b (AOP2014/P1101) in the Peginvera study” by Them et al This abstract describes the chromosomal analysis of PV patients on the Peginvera study (a study investigating a long-acting IFNa which can be […]

Proposed Revision of WHO Diagnostic Criteria for MPNs

Synopsis of: An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for Myeloproliferative Neoplasms by Dr. Angela Fleischman We are rapidly learning more about the mutations acquired by cancer cells, this is particularly evident in blood malignancies. Most recently, calreticulin mutations have been identified in the majority of […]

PV Reporter is proud to introduce Dr Angela Fleischman as consulting physician

Dr. Angela Fleischman, Assistant Professor, Dept. of Medicine, Hematology/Oncology, UC Irvine Health Dr. Fleischman’s Bio: I am a physician-scientist dedicated to a life-long career investigating MPN, integrating my research with the clinical care of patients with this disease. My overarching goal is to identify what drives disease initiation in MPN and to ultimately translate my […]

 
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