NAC N-acetylcysteine Supplement may benefit MPN patients

by Deb Wesloh N-acetylcysteine (NAC) supplement has shown to have Antioxidant and Anti-inflammatory Properties Polycythemia vera, essential thrombocythemia and myelofibrosis make up a class of blood cancers called myeloproliferative neoplasms or MPNs.  MPNs are characterized by the over-production of red or white blood cells or platelets in the bone marrow. MPNs increase the risk of […]

Ocular Manifestations in Patients with Philadelphia Negative Myeloproliferative Neoplasms

Abstract: The major complications of Philadelphia‐negative (Ph‐Negative) myeloproliferative neoplasms (MPNs) are thrombosis, haemorrhage and leukemic transformation. As systemic and haematological diseases, MPNs have the potential to affect many tissues and organs. Some complications lead to the diagnosis of MPNs, but other signs and symptoms are often misdiagnosed or neglected as a sign of MPN disease. […]

Nutrition and Diet May Reduce Chronic Inflammation while Improving Symptom Burden in MPN Patients

Nutrition for MPN Patients Part 3 in a New Series – “Addressing MPN Symptoms” (2019) We know diet plays a role in inflamation.  Chronic inflammation may be an important driving force for clonal evolution and disease progression in myeloproliferative neoplasms (MPNs), essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF).  So with that in mind, eating a […]

The Fleischman Lab Continues Investigating the Role of Inflammation in MPN

2015 MPN Research Update by Dr. Angela Fleischman We are continuing to work on the role of inflammation in MPN.  The human immune system turns on the immune response when it recognizes invaders such as bacteria or viruses by producing inflammatory proteins, also called cytokines.  Cytokines are helpful to fight infection but if the immune […]

High levels of Inflammation disrupt normal blood formation potentially leading to leukemia

Indiana University researchers identify events causing bone marrow inflammation leading to blood disorders Like a line of falling dominos, a cascade of molecular events in the bone marrow produces high levels of inflammation that disrupt normal blood formation and lead to potentially deadly disorders including leukemia. “It has been known for years that there are […]

Bone & Joint Pain in MPN Patients Explained

Pearls of wisdom (1995) by the late Dr. Gilbert Dear Members:  For your information re bone and joint pains in MPN.  Several of you have mentioned that you suffer from bone and/or joint pains – sometimes attributed to arthritis.  I have seen a number of patients who have this complaint and it has been related […]

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