MPNs and Insomnia: Tips for Better Sleep

65% of Myeloproliferative Neoplasm, Cancer Patients report Sleep Problems Part 5 in a New Series – “Addressing MPN Symptoms” (2019) by Heidi Cascarano Many people struggle with sleep disturbances, and we all know that lack of quality sleep can lead to daytime fatigue, diminished quality of life, and other health problems.  What’s worse is that […]

Targeted therapies for Myeloproliferative Neoplasms MPNs

Abstract The discovery of JAK2V617F and the demonstration that BCR-ABL-negative myeloproliferative neoplasms (MPNs) are driven by abnormal JAK2 activation have led to advances in diagnostic algorithms, prognosis and ultimately also treatment strategies. The JAK 1/2 inhibitor ruxolitinib was a pivotal moment in the treatment of MPNs, representing the first targeted treatment in this field. Despite a […]

 
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