Episode 1 of 3 in Patients are Asking Series What symptoms should I look for to see if I might be progressing from polycythemia vera to myelofibrosis? When would you typically recommend Next Generation Sequencing (NGS) and what are the benefits? Why does bone & joint pain occur and what are some possible solutions? Dr. […]
New MPN Drug Treatments in Development
by David Wallace What are some of the latest combination drug treatments in development for MPN? Find out the latest on combination add-on strategies to JAK inhibitors and other new agents. Two combination therapies for Myelofibrosis look promising as they move into phase 3 clinical trials. They include adding CPI-0610 (a bromodomain, BET, inhibitor) and […]
MPN Focus Fall2016 – MD Anderson Newsletter – Itching Tips, PV Reporter
The Zyrtec and Zantac combo is helping MPN patients get relief from Itching! Note: Download PDF is a small icon on the top of the gray title bar, just below.
Mast Cells and Histamine in MPN Related Itching Explained
Updated Feb. 21, 2025 MPN patients suffering from intense itching have long relied on a combination of over-the-counter medications for relief, commonly known as the “Z and Z combo” – Zyrtec (cetirizine) and Zantac (ranitidine). However, in 2020, Zantac faced a widespread recall due to concerns over potential carcinogenic contaminants. This development left many MPN […]
