by David Wallace For many people living with polycythemia vera (PV) and other myeloproliferative neoplasms, stepping into a warm shower can trigger an unbearable sensation that has nothing to do with the water temperature. Aquagenic pruritus (intense itching that occurs after contact with water) remains one of the most frustrating symptoms patients face, affecting nearly […]
Polycythemia Vera Brain Fog
by David Wallace updated July 10, 2025 This is no wonderful “epiphany moment” article, just a quick report on a real myeloproliferative neoplasm (MPN) symptom I experience from time to time. Many mornings, I make a healthy smoothie to get me up and rolling. This morning I grabbed the wrong ingredient and sprinkled it in […]
Rusfertide Cuts Phlebotomies by 77% in Polycythemia Vera
by David Wallace Key Points Rusfertide achieved clinical response in 77% of patients compared to 33% with placebo in the Phase 3 VERIFY trial The drug significantly reduced the number of blood draws needed each year and decreased PV-related symptoms Rusfertide maintained hematocrit levels below 45% and reduced or eliminated the need for phlebotomy Safety […]
What Are The Key Factors in Predicting Polycythemia Vera Progression?
by David Wallace A new study has shed light on the factors that may predict polycythemia vera (PV) disease progression. The REVEAL study, presented at the 2024 European Hematology Association Congress, has identified five key characteristics that could help doctors better understand which patients are at higher risk of their condition worsening over time. Polycythemia […]
Polycythemia Vera Exercise Recommendations
Abstract Background Exercise therapy during cancer treatment reduces symptom burden and improves quality of life (QoL). Polycythemia vera (PV) is a myeloproliferative neoplasia associated with good overall survival (up to decades) but a significant symptom burden, including thromboembolic events and dysesthesias. There are no specific exercise recommendations for patients with PV. Thus, we aimed to […]
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